A study published in Nature has provided new insights into the evolutionary patterns of metastatic bladder…
oncology
Coffee consumption and colorectal cancer: Potential mechanisms underlying protective effects
Colorectal cancer (CRC) is one of the most commonly diagnosed malignancies worldwide and remains a major…
Cancer-associated fibroblast–treg cell crosstalk in lung adenocarcinoma: emerging mechanisms and therapeutic implications
Introduction The tumor microenvironment (TME) is a highly complex and dynamic ecosystem comprising malignant cells, stromal cells, extracellular matrix (ECM), and diverse…
New molecular target offers hope for treating aggressive triple-negative breast cancer
Australian researchers have identified a molecular pathway that appears to regulate the spread of triple-negative breast cancer (TNBC), raising the…
Obesity linked to distinct molecular changes that may promote invasive breast cancer
A new study published in The American Journal of Pathology has identified a distinct molecular program linking obesity with the…
ARID1A-mediated chromatin remodeling in gastric epithelial recovery: An emerging barrier against gastric tumorigenesis
The gastric epithelium is continuously exposed to chemical, microbial, and mechanical insults, necessitating highly coordinated processes of tissue…
Chronic stress may help tumors escape immune attack through gut microbes
A new preclinical study has uncovered an unexpected link between chronic psychological stress, gut microbes, and…
First-in-human trial of IMA401 shows promise in advanced solid tumors
A first-in-human phase 1 clinical trial published in Nature Medicine has reported encouraging early results for…
Personalized DNA vaccine shows promise in aggressive glioblastoma
A personalized DNA-based cancer vaccine has shown encouraging early results in patients with one of the…
Metformin mimics exercise-induced metabolic pathways in prostate cancer patients
A widely prescribed antidiabetic drug, metformin, may help reproduce key metabolic effects of physical exercise in…