Obesity is a chronic, multifactorial disease characterized by excessive or abnormal adiposity that adversely affects health…
Mini Reviews
Semaglutide and cardiovascular risk reduction in overweight or obesity: Evidence from the SELECT trial
Semaglutide reduced the risk of major adverse cardiovascular events (MACE) by 20% in adults with overweight…
Coffee consumption and colorectal cancer: Potential mechanisms underlying protective effects
Colorectal cancer (CRC) is one of the most commonly diagnosed malignancies worldwide and remains a major…
Cancer-associated fibroblast–treg cell crosstalk in lung adenocarcinoma: emerging mechanisms and therapeutic implications
Introduction The tumor microenvironment (TME) is a highly complex and dynamic ecosystem comprising malignant cells, stromal cells, extracellular matrix (ECM), and diverse…
Intermittent fasting in older adults: Does advancing age change the risk–benefit balance?
Introduction Population aging is accompanied by an increasing burden of chronic diseases and multimorbidity. Age is…
Potassium-competitive acid blockers versus proton pump inhibitors in dual antiplatelet therapy: Efficacy, safety and gastroprotection
Potassium-competitive acid blockers versus proton pump inhibitors in dual antiplatelet therapy: Efficacy, safety and gastroprotection Introduction …
Tirzepatide beyond glycemic control: Expanding therapeutic benefits
Emerging evidence indicates that the therapeutic benefits of tirzepatide extend beyond glycemic control, with clinically relevant effects on…
Eucommiae cortex polysaccharides as a gut–brain axis modulator in Alzheimer’s disease
Alzheimer’s disease (AD) is the most common neurodegenerative disorder and the leading cause of dementia, accounting…
Dietary index for gut microbiota and coronary heart disease: Emerging evidence on mortality risk
Introduction Coronary heart disease (CHD) remains one of the leading causes of morbidity and mortality worldwide,…
ARID1A-mediated chromatin remodeling in gastric epithelial recovery: An emerging barrier against gastric tumorigenesis
The gastric epithelium is continuously exposed to chemical, microbial, and mechanical insults, necessitating highly coordinated processes of tissue…